MIB1 Polyclonal Antibody

Background:
This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).

Research Area: Cancer, Stem Cells

Synonyms:
MIB1, DIP-1, DIP1, LVNC7, MIB, ZZANK2, ZZZ6

Immunogen: Recombinant fusion protein of human MIB1 (NP_065825.1).

Swissprot: Q86YT6
Gene ID: 57534

Calculated MW: 110 kDa
Observed MW: 110 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.