MICALL2 polyclonal, anti-human

Protein Family: Cytoskeleton Proteins

Pathway and Disease: Signaling Molecules and Interaction

Description:
MICAL-like protein 2 (MICALL2) is a cytosolic protein that interacts with neuronal plexin A (PlexA) receptors. Members of the semaphorin family of secreted and transmembrane proteins utilize plexins as neuronal receptors to signal repulsive axon guidance. In addition to containing several domains known to interact with cytoskeletal components, MICALL2 has a flavoprotein monooxygenase domain, the integrity of which is required for Sema-1a-PlexA repulsive axon guidance. Monooxygenase inhibitors abrogate semaphorin-mediated axonal repulsion.

Alternate Names: MICAL-like protein 2, MICALL2

Application Notes: E: 1:10,000-1:50,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: Q8IY33

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human MICALL2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.