MICB polyclonal, anti-human, rat

Quantity: 100 µg

Background:
MHC class I polypeptide-related sequence B is a protein that in humans is encoded by the MICB gene. This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

Description:
Rabbit IgG polyclonal antibody for MHC class I polypeptide-related sequence B (MICB) detection. Tested with WB in Human, Rat.

Synonyms:
MHC class I chain related protein B2 antibody, MHC class I mic B antigen antibody, MHC class I polypeptide related sequence B antibody, MHC class I polypeptide-related sequence B antibody, MIC B antibody, MIC-B antibody, MICB antibody, MICB_HUMAN antibody, PERB11.2 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human MICB (23-48aa AEPHSLRYNLMVLSQDESVQSGFLAE).A synthetic peptide corresponding to a sequence at the N-terminus of human MICB (23-48aa AEPHSLRYNLMVLSQDESVQSGFLAE).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.