MID1 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13465b
Background:
The protein encoded by this gene is a member of thetripartite motif (TRIM) family, also known as the 'RING-Bbox-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIMmotif includes three zinc-binding domains, a RING, a B-box type 1and a B-box type 2, and a coiled-coil region. This protein formshomodimers which associate with microtubules in the cytoplasm. Theprotein is likely involved in the formation of multiproteinstructures acting as anchor points to microtubules. Mutations inthis gene have been associated with the X-linked form of Opitzsyndrome, which is characterized by midline abnormalities such ascleft lip, laryngeal cleft, heart defects, hypospadias, andagenesis of the corpus callosum. This gene was also the firstexample of a gene subject to X inactivation in human while escapingit in mouse. Multiple different transcript variants are generatedby alternate splicing; however, the full-length nature of some ofthe variants has not been determined.
Other Names:
E3 ubiquitin-protein ligase Midline-1, 632-, Midin, Putative transcription factor XPRF, RING finger protein 59, RING finger protein Midline-1, Tripartite motif-containing protein 18, MID1, FXY, RNF59, TRIM18, XPRF
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13465b was selected from the C-term region of MID1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MID1
Gene ID: 4281
Primary Accession: O15344
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a member of thetripartite motif (TRIM) family, also known as the 'RING-Bbox-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIMmotif includes three zinc-binding domains, a RING, a B-box type 1and a B-box type 2, and a coiled-coil region. This protein formshomodimers which associate with microtubules in the cytoplasm. Theprotein is likely involved in the formation of multiproteinstructures acting as anchor points to microtubules. Mutations inthis gene have been associated with the X-linked form of Opitzsyndrome, which is characterized by midline abnormalities such ascleft lip, laryngeal cleft, heart defects, hypospadias, andagenesis of the corpus callosum. This gene was also the firstexample of a gene subject to X inactivation in human while escapingit in mouse. Multiple different transcript variants are generatedby alternate splicing; however, the full-length nature of some ofthe variants has not been determined.
Other Names:
E3 ubiquitin-protein ligase Midline-1, 632-, Midin, Putative transcription factor XPRF, RING finger protein 59, RING finger protein Midline-1, Tripartite motif-containing protein 18, MID1, FXY, RNF59, TRIM18, XPRF
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13465b was selected from the C-term region of MID1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MID1
Gene ID: 4281
Primary Accession: O15344
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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