Midkine polyclonal, anti-human

Background:
Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation.

Synonyms: MK1,  NEGF2, MDK

Cellular Location: Secreted

Immunogen:
A synthetic peptide of human Midkine

Gene Symbol: Midkine

Gene ID: 4192

Swiss prot: P21741

Calculated MW: 16kDa

Recommended dilution:
WB 1:500-2000, IHC 1:25-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.