MIDN Polyclonal Antibody

Background:
Expression of themidnolingene is developmentally regulated: it is strongly expressed at the mesencephalon (midbrain) of the embryo in day 12.5 (E12.5) mice. Themidnolinencodes a protein of 508 amino acids (aa), which contains a Ubiquitin-like domain. The intracellular distribution of themidnolinwas studied by usingmidnolin-green fluorescent protein (GFP) fusion proteins.Midnolinwas found to be localized in the nucleus and nucleolus, but not in the cytoplasm. The nucleolar localization signal was determined to be a 28aa peptide located at the C-terminal region of themidnolin.May be involved in regulation of genes related to neurogenesis in the nucleolus

Research Area: Cell Biology

Synonyms:
Midbrain nucleolar protein, midn, MIDN, Midnolin

Immunogen: Synthetic peptide of human MIDN

Swissprot: Q504T8
Gene Accession: NP_796375

Calculated MW: 49 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.