MIF polyclonal, anti-human

Quantity: 100 µg

Background:
Macrophage migration inhibitory factor (MIF or MMIF), also known as GIF, is a protein that in humans is encoded by the MIF gene. It is a cytokine released by T-lymphocytes, macrophages, and the pituitary gland that serves to integrate peripheral and central inflammatory responses. MIF gene has 3 exons separated by introns of only 189 and 95 bp, and covers less than 1 kb. The localization of the human gene for MIF is to chromosome 22q11.2. MIF plays a critical role in inflammatory diseases and atherogenesis. It is also involved in cell-mediated immunity and immunoregulation. MIF plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids.

Description:
Rabbit IgG polyclonal antibody for Macrophage migration inhibitory factor (MIF) detection. Tested with WB, IHC-P, ICC in Human.

Synonyms:
acrophage migration inhibitory factor (glycosylation-inhibiting factor) antibody, GIF antibody, GLIF antibody, Glycosylation inhibiting factor antibody, Glycosylation-inhibiting factor antibody, L-dopachrome isomerase antibody, L-dopachrome tautomerase antibody, Macrophage migration inhibitory factor antibody, Macrophage migration inhibitory factor antibody, MIF antibody, MIF antibody, MIF protein antibody, MIF_HUMAN antibody, MMIF antibody, Phenylpyruvate tautomerase antibody, Phenylpyruvate tautomerase antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human MIF recombinant protein (Position: P2-A115). Human MIF shares 89% and 90% amino acid (aa) sequence identity with mouse and rat MIF respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P, ICC

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.