MIF polyclonal, anti-human, mouse, rat, dog, pig , bovine

Protein Family: Enzymes

Pathway and Disease: Amino Acid Metabolism

Description:
Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine. MIF is involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Genetic variations in MIF are associated with susceptibility to rheumatoid arthritis systemic juvenile (RASJ). RASJ is an inflammatory articular disorder with systemic-onset beginning before the age of 16.

Alternate Names: Macrophage migration inhibitory factor, MIF, Phenylpyruvate tautomerase, L-dopachrome tautomerase, L-dopachrome isomerase, Glycosylation-inhibiting factor, GIF, GLIF, MMIF

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500

Accession No.: P14174

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human MIF.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.