MIP-1 alpha rat active recombinant protein
€295.00
In stock
SKU
600380
Protein Family: Cytokines
Pathway and Disease: Immune System, Signal Transduction, Signaling Molecules and Interaction
Alternate Names: C-C motif chemokine 3, small-inducible cytokine A3, macrophage inflammatory protein 1-alpha, MIP-1-alpha, tonsillar lymphocyte LD78 alpha protein, G0/G1 switch regulatory protein 19-1, G0S19-1 protein, SIS- beta, PAT 464.1, MIP-1-alpha(4-69), LD78-alpha(4-69), CCL3, G0S19-1, MIP1A, SCYA3Description:
Macrophage Inflammatory Protein-1 alpha (MIP-1alpha), also known as CCL3, is produced by macrophages and is thought to induce inflammatory responses, including superoxide production by neutrophils. MIP-1alpha can exist as a naturally occurring heterodimer with MIP-1beta and has been shown to have antiviral activity against HSV-1. Rat MIP-1 alpha is produced in E.coli. Recombinant rat MIP-1 alpha is a non-glycosylated protein, containing 69 amino acids, with a molecular weight of 7.8 kDa.
Source: E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.
Applications: E, WB
Application Notes:
The activity is determined by the ability to chemoattract human PBMCs at 1-10 ng/mL. Specific activity: 1 x 10e6 units/mg
Accession No.: P50229
MW: 7800 Da
Sequence:
APYGADTPTA CCFSYGRQIP RKFIADYFET SSLCSQPGVI FLTKRNRQIC ADPKETWVQE YITELELNA
Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 20 ug of lyophilized protein. Reconstitute with 0.2 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
Pathway and Disease: Immune System, Signal Transduction, Signaling Molecules and Interaction
Alternate Names: C-C motif chemokine 3, small-inducible cytokine A3, macrophage inflammatory protein 1-alpha, MIP-1-alpha, tonsillar lymphocyte LD78 alpha protein, G0/G1 switch regulatory protein 19-1, G0S19-1 protein, SIS- beta, PAT 464.1, MIP-1-alpha(4-69), LD78-alpha(4-69), CCL3, G0S19-1, MIP1A, SCYA3Description:
Macrophage Inflammatory Protein-1 alpha (MIP-1alpha), also known as CCL3, is produced by macrophages and is thought to induce inflammatory responses, including superoxide production by neutrophils. MIP-1alpha can exist as a naturally occurring heterodimer with MIP-1beta and has been shown to have antiviral activity against HSV-1. Rat MIP-1 alpha is produced in E.coli. Recombinant rat MIP-1 alpha is a non-glycosylated protein, containing 69 amino acids, with a molecular weight of 7.8 kDa.
Source: E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.
Applications: E, WB
Application Notes:
The activity is determined by the ability to chemoattract human PBMCs at 1-10 ng/mL. Specific activity: 1 x 10e6 units/mg
Accession No.: P50229
MW: 7800 Da
Sequence:
APYGADTPTA CCFSYGRQIP RKFIADYFET SSLCSQPGVI FLTKRNRQIC ADPKETWVQE YITELELNA
Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 20 ug of lyophilized protein. Reconstitute with 0.2 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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