Bcl-2 (phospho Ser70) polyclonal, anti-human, primate
€470.00
In stock
SKU
AC-AP66963
Background:
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
Other Names:
BCL2; Apoptosis regulator Bcl-2
Antigen Type: synthetic peptide
Antigen Type: BCL2
Gene ID: 596
Primary Accession: P10415
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
Other Names:
BCL2; Apoptosis regulator Bcl-2
Antigen Type: synthetic peptide
Antigen Type: BCL2
Gene ID: 596
Primary Accession: P10415
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