MIP-3-beta mouse active recombinant protein
€295.00
In stock
SKU
600206
Protein Family: Cytokines
Pathway and Disease: Immune System, Signal Transduction, Signaling Molecules and Interaction
Alternate Names: C-C motif chemokine 19, small-inducible cytokine A19, macrophage inflammatory protein 3 beta, Mip-3-beta, EBI1- ligand chemokine, ELC, Beta chemokine exodus-3, CK beta-11, CCL19, ELC, MIP3B, SCYA19Description:
Macrophage inflammatory protein 3 beta (MIP-3-alpha or C-C motif chemokine 19) is is a cytokine that plays a role in inflammatory and immunological responses as well as normal lymphocyte recirculation and homing. MIP-3-beta also is important in T-cell trafficking in the thymus, and T-cell and B-cell migration to secondary lymphoid organs. MIP-3-beta specifically binds to the chemokine receptor CCR7. Recombinant Mouse MIP-3 alpha has a MW of 7.9 kDa, comprised of 70 amino acids.
Recombinant Mouse Macrophage Inflammatory Protein-3-beta (CCL 19) is an important chemoattractant for dendritic cells, antigen-engaged B-cells and effector-memory T-cells, signaling specifically through the CCR7 receptor. This cytokine plays a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Recombinant mouse MIP-3-beta is a polypeptide chain consisting of 83 amino acids with a MW of 9.2 kDa.
Source: E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
Applications: E, WB
Application Notes:
Recombinant mouse MIP-3-beta induces chemotaxis of human T- cells in a concentration range of 8 – 80 ng/ml.
Accession No.: O70460
MW: 9200 Da
Sequence:
GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS
Purity:
Purity > 98% as determined by analytical HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 20 ug of lyophilized protein. Reconstitute with 0.2 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
Pathway and Disease: Immune System, Signal Transduction, Signaling Molecules and Interaction
Alternate Names: C-C motif chemokine 19, small-inducible cytokine A19, macrophage inflammatory protein 3 beta, Mip-3-beta, EBI1- ligand chemokine, ELC, Beta chemokine exodus-3, CK beta-11, CCL19, ELC, MIP3B, SCYA19Description:
Macrophage inflammatory protein 3 beta (MIP-3-alpha or C-C motif chemokine 19) is is a cytokine that plays a role in inflammatory and immunological responses as well as normal lymphocyte recirculation and homing. MIP-3-beta also is important in T-cell trafficking in the thymus, and T-cell and B-cell migration to secondary lymphoid organs. MIP-3-beta specifically binds to the chemokine receptor CCR7. Recombinant Mouse MIP-3 alpha has a MW of 7.9 kDa, comprised of 70 amino acids.
Recombinant Mouse Macrophage Inflammatory Protein-3-beta (CCL 19) is an important chemoattractant for dendritic cells, antigen-engaged B-cells and effector-memory T-cells, signaling specifically through the CCR7 receptor. This cytokine plays a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Recombinant mouse MIP-3-beta is a polypeptide chain consisting of 83 amino acids with a MW of 9.2 kDa.
Source: E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
Applications: E, WB
Application Notes:
Recombinant mouse MIP-3-beta induces chemotaxis of human T- cells in a concentration range of 8 – 80 ng/ml.
Accession No.: O70460
MW: 9200 Da
Sequence:
GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS
Purity:
Purity > 98% as determined by analytical HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 20 ug of lyophilized protein. Reconstitute with 0.2 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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