MITF monoclonal, anti-human, mouse, rat
€0.00
In stock
SKU
AC-AM8516b
Catalog Number: AC-AM8516b
Size: 50 µl, 200 µl
Isotype: mouse IgG1,k
Clone Name: 1607CT834.207.47
Applications: WB
Datasheet
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Size: 50 µl, 200 µl
Isotype: mouse IgG1,k
Clone Name: 1607CT834.207.47
Applications: WB
Datasheet
Request Information
Background:
Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'- CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest- derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Other Names:
Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32, bHLHe32, MITF, BHLHE32
Target/Specificity:
This MITF antibody is generated from a mouse immunized with a recombinant protein of human MITF.
Antigen Type: Recombinant Protein
Gene Name: MITF {ECO:0000303|PubMed:8069297, ECO:0000312|HGNC:HGNC:7105}
Gene ID: 4286
Primary Accession: O75030
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'- CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest- derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Other Names:
Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32, bHLHe32, MITF, BHLHE32
Target/Specificity:
This MITF antibody is generated from a mouse immunized with a recombinant protein of human MITF.
Antigen Type: Recombinant Protein
Gene Name: MITF {ECO:0000303|PubMed:8069297, ECO:0000312|HGNC:HGNC:7105}
Gene ID: 4286
Primary Accession: O75030
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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