MITF polyclonal, anti-human, mouse

Background:
This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Synonyms: CMM8, COMMAD, MI, WS2, WS2A, bHLHe32

Cellular Location: Nucleus

Immunogen:
Recombinant protein of human MITF

Gene Symbol: MITF

Gene ID: 4286

Swiss prot: O75030

Calculated MW: 59kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.