MITF polyclonal (N-term), anti-human
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In stock
SKU
AC-AP11559a
Catalog Number: AC-AP11559a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18810
Applications: WB, IF, FC
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18810
Applications: WB, IF, FC
Datasheet
Request Information
Background:
This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Other Names:
Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32, bHLHe32, MITF, BHLHE32
Target/Specificity:
This MITF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-28 amino acids from the N-terminal region of human MITF.
Antigen Region:
1-28
Antigen Type: Synthetic Peptide
Gene Name: MITF {ECO:0000303|PubMed:8069297, ECO:0000312|HGNC:HGNC:7105}
Gene ID: 4286
Primary Accession: O75030
NCBI Accession: NP_000239.1;NP_001171896.1;NP_006713.1;NP_937801.1;NP_937802.1;NP_937820.1;NP_937821.2
Other Accession: Q08874; NP_937802.1; NP_001171896.1; O88368
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Other Names:
Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32, bHLHe32, MITF, BHLHE32
Target/Specificity:
This MITF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-28 amino acids from the N-terminal region of human MITF.
Antigen Region:
1-28
Antigen Type: Synthetic Peptide
Gene Name: MITF {ECO:0000303|PubMed:8069297, ECO:0000312|HGNC:HGNC:7105}
Gene ID: 4286
Primary Accession: O75030
NCBI Accession: NP_000239.1;NP_001171896.1;NP_006713.1;NP_937801.1;NP_937802.1;NP_937820.1;NP_937821.2
Other Accession: Q08874; NP_937802.1; NP_001171896.1; O88368
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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