Mitofilin polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60403
Background:
Cristae are highly folded inner mitochondrial membrane compartments that are studded with cytochromes and ATP synthase proteins and function to provide a large surface area upon which cellular respiration can occur. Mitofilin, also known as IMMT, HMP, PIG4 or P87/89, is a 758 amino acid inner mitochondrial membrane protein that is preferentially expressed in heart tissue. Existing as three alternatively spliced isoforms, Mitofilin functions to control mitochondrial cristae morphology, including the formation and organization of cristae junctions and normal tubular cristae. Due to its role in mediating cristae structure and function, Mitofilin is essential for normal mitochondrial function and is, thus, critical to overall cell survival.
Alternative Name:
Mitochondrial inner membrane protein, Cell proliferation-inducing gene 4/52 protein, Mitofilin, p87/89, IMMT, HMP, MINOS2, PIG4, PIG52
Application Dilution: WB: 1:500~1:1000
Specificity: Mitofilin polyclonal antibody detects endogenous levels of Mitofilin protein.
Immunogen:
A synthetic peptide corresponding to residues in Human Mitofilin.
MW: ~ 84 kDa
Swis Prot.: Q16891
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Cristae are highly folded inner mitochondrial membrane compartments that are studded with cytochromes and ATP synthase proteins and function to provide a large surface area upon which cellular respiration can occur. Mitofilin, also known as IMMT, HMP, PIG4 or P87/89, is a 758 amino acid inner mitochondrial membrane protein that is preferentially expressed in heart tissue. Existing as three alternatively spliced isoforms, Mitofilin functions to control mitochondrial cristae morphology, including the formation and organization of cristae junctions and normal tubular cristae. Due to its role in mediating cristae structure and function, Mitofilin is essential for normal mitochondrial function and is, thus, critical to overall cell survival.
Alternative Name:
Mitochondrial inner membrane protein, Cell proliferation-inducing gene 4/52 protein, Mitofilin, p87/89, IMMT, HMP, MINOS2, PIG4, PIG52
Application Dilution: WB: 1:500~1:1000
Specificity: Mitofilin polyclonal antibody detects endogenous levels of Mitofilin protein.
Immunogen:
A synthetic peptide corresponding to residues in Human Mitofilin.
MW: ~ 84 kDa
Swis Prot.: Q16891
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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