Mitofusin-1 polyclonal, anti-human, mouse, rat

Protein Family: Enzymes, GTP-binding Proteins

Pathway and Disease: Cancers, Membrane Transport

Description:
Mitofusin-1 (MFN1) is an essential transmembrane GTPase that mediates mitochondrial fusion, which constitutes an important step in mitochondria morphology drived by a fusion and fission balance. MFN1 acts independently of the cytoskeleton by forming homo- and heteromultimers with MFN2. MFN1 is ubiquitously expressed.

Alternate Names: Mitofusin-1, Transmembrane GTPase MFN1, Fzo homolog, MFN1

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; FC: 1:50-1:200

Accession No.: Q8IWA4

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human MFN1.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.