Mitofusin-2 polyclonal, anti-human, mouse, rat
€445.00
In stock
SKU
251872
Protein Family: Enzymes, GTP-binding Proteins
Pathway and Disease: Neurodegenerative Disorders
Description:
Mitofusin-2 is as essential transmembrane GTPase which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. Mitofusin-2 acts independently of the cytoskeleton, plays a central role in mitochondrial metabolism, and is associated with obesity and/or apoptosis processes. Defects in mitofusin-2 are the cause of Charcot-Marie-Tooth disease type 2A2 (CMT2A2). CMT2A2 is a form of Charcot-Marie-Tooth disease, the most common inherited disorder of the peripheral nervous system.
Alternate Names: Mitofusin-2, Transmembrane GTPase MFN2, MFN2, CPRP1, KIAA0214
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: O95140
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human mitofusin-2.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Neurodegenerative Disorders
Description:
Mitofusin-2 is as essential transmembrane GTPase which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. Mitofusin-2 acts independently of the cytoskeleton, plays a central role in mitochondrial metabolism, and is associated with obesity and/or apoptosis processes. Defects in mitofusin-2 are the cause of Charcot-Marie-Tooth disease type 2A2 (CMT2A2). CMT2A2 is a form of Charcot-Marie-Tooth disease, the most common inherited disorder of the peripheral nervous system.
Alternate Names: Mitofusin-2, Transmembrane GTPase MFN2, MFN2, CPRP1, KIAA0214
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: O95140
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human mitofusin-2.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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