MKL1 polyclonal (Center), anti-human
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In stock
SKU
AC-AP18838C
Catalog Number: AC-AP18838C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB39491
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB39491
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia.
Other Names:
MKL/myocardin-like protein 1, Megakaryoblastic leukemia 1 protein, Megakaryocytic acute leukemia protein, Myocardin-related transcription factor A, MRTF-A, MKL1, KIAA1438, MAL
Target/Specificity:
This MKL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 497-525 amino acids from the Central region of human MKL1.
Antigen Region:
497-525
Antigen Type: Synthetic Peptide
Gene Name: MRTFA (HGNC:14334)
Gene ID: 57591
Primary Accession: Q969V6
NCBI Accession: NP_065882.1
Other Accession: NP_065882.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia.
Other Names:
MKL/myocardin-like protein 1, Megakaryoblastic leukemia 1 protein, Megakaryocytic acute leukemia protein, Myocardin-related transcription factor A, MRTF-A, MKL1, KIAA1438, MAL
Target/Specificity:
This MKL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 497-525 amino acids from the Central region of human MKL1.
Antigen Region:
497-525
Antigen Type: Synthetic Peptide
Gene Name: MRTFA (HGNC:14334)
Gene ID: 57591
Primary Accession: Q969V6
NCBI Accession: NP_065882.1
Other Accession: NP_065882.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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