ML-IAP Polyclonal Antibody

Background:
baculoviral IAP repeat containing 7(BIRC7) Homo sapiens This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013],

Alternative Names:
BIRC7, KIAP, LIVIN, MLIAP, RNF50, Baculoviral IAP repeat-containing protein 7, Kidney inhibitor of apoptosis protein, KIAP, Livin, Melanoma inhibitor of apoptosis protein, ML-IAP, RING finger protein

Immunogen: The antiserum was produced against synthesized peptide derived from human ML-IAP. AA range:162-211

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 21

GeneID: BIRC7

Storage: -20°C/1 year

NOTE: For Research Use Only