MLF1 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP21309b
Catalog Number: AC-AP21309b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB52389
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB52389
Applications: WB
Datasheet
Request Information
Background:
Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Other Names:
Myeloid leukemia factor 1, Myelodysplasia-myeloid leukemia factor 1, MLF1
Target/Specificity:
This MLF1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 232-266 amino acids from the C-terminal region of human MLF1.
Gene Name: MLF1
Gene ID: 4291
Primary Accession: P58340
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Other Names:
Myeloid leukemia factor 1, Myelodysplasia-myeloid leukemia factor 1, MLF1
Target/Specificity:
This MLF1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 232-266 amino acids from the C-terminal region of human MLF1.
Gene Name: MLF1
Gene ID: 4291
Primary Accession: P58340
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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