MLH1 (clone 2B3-H6-C11), anti-human

Background:
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC).It is a human homolog of the E. coli DNA mismatch repair gene mutL,consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC.Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described,but their full-length natures have not been determined.[provided by RefSeq,Nov 2009]

Synonyms: COCA2, FCC2, hMLH1, HNPCC, HNPCC2

Cellular Location: Nucleus

Immunogen:
Purified recombinant human MLH1 protein fragments expressed in E.coli.

Gene Symbol: MLH1

Gene ID: 4292

Swiss prot: P40692

Calculated MW: 85kDa

Recommended dilution:
WB 1:500

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.