MLH1 (clone 4C1) mouse monoclonal, anti-human, monkey

Backgroud: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined.

Synonyms: MLH1, COCA2, DNA mismatch repair protein Mlh1, MutL protein homolog 1

Gene Name: MLH1

Gene ID: 4292

SwissProt ID: P40692

Purification: Ascitic Fluid

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.