MLH1 Polyclonal Antibody

Background:
mutL homolog 1(MLH1) Homo sapiens This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009],

Alternative Names:
MLH1, COCA2, DNA mismatch repair protein Mlh1, MutL protein homolog 1

Immunogen: The antiserum was produced against synthesized peptide derived from human MLH1. AA range:441-490

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 85

GeneID: MLH1

Storage: -20°C/1 year

NOTE: For Research Use Only