MLH1 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP11686c
Catalog Number: AC-AP11686c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18813
Applications: FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18813
Applications: FC, WB
Datasheet
Request Information
Background:
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
Other Names:
DNA mismatch repair protein Mlh1, MutL protein homolog 1, MLH1, COCA2
Target/Specificity:
This MLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-480 amino acids from the Central region of human MLH1.
Antigen Region:
452-480
Antigen Type: Synthetic Peptide
Gene Name: MLH1
Gene ID: 4292
Primary Accession: P40692
NCBI Accession: NP_000240.1;NP_001161089.1;NP_001161090.1;NP_001161091.1;NP_001245200.1;NP_001245202.1;NP_001245203.1
Other Accession: NP_001161090.1;NP_001161091.1;NP_000240.1;NP_001161089.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
Other Names:
DNA mismatch repair protein Mlh1, MutL protein homolog 1, MLH1, COCA2
Target/Specificity:
This MLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-480 amino acids from the Central region of human MLH1.
Antigen Region:
452-480
Antigen Type: Synthetic Peptide
Gene Name: MLH1
Gene ID: 4292
Primary Accession: P40692
NCBI Accession: NP_000240.1;NP_001161089.1;NP_001161090.1;NP_001161091.1;NP_001245200.1;NP_001245202.1;NP_001245203.1
Other Accession: NP_001161090.1;NP_001161091.1;NP_000240.1;NP_001161089.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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