MLH3 Polyclonal Antibody

Background:
mutL homolog 3(MLH3) Homo sapiens This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008],

Alternative Names:
MLH3, DNA mismatch repair protein Mlh3, MutL protein homolog 3

Immunogen: The antiserum was produced against synthesized peptide derived from human MLH3. AA range:521-570

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 164

GeneID: MLH3

Storage: -20°C/1 year

NOTE: For Research Use Only