MLK3 (Phospho Thr277+Ser281) Rabbit polyclonal antibody, anti-human, mouse, rat

MLK3 (Phospho Thr277+Ser281) Rabbit polyclonal antibody, anti-human, mouse, rat

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In stock
SKU
BT-AP03627
Catalog Number: BT-AP03627
Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human, mouse, rat
Application(s): WB, ELISA
Datasheet
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Background:
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase| and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate| and activates IkappaB kinase alpha and beta| and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.

Research Area: Signal transduction

Synonyms: MLK3 , Phospho Thr277+Ser281, Mitogen-activated protein kinase kinase kinase 11, EC 2.7.11.25, Mixed lineage kinase 3, Src-homology 3 domain-containing proline-rich kinase

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year
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