MLK4 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP8006a
Catalog Number: AC-AP8006a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB12543
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB12543
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Mixed-lineage kinases (MLKs) function as mitogen-activated protein kinase kinase kinases (MAP3Ks), activating the p38 and JNK signaling cascades. Systematic mutational analyses of tyrosine kinases reveal that a minimum of 30% of colorectal cancer contain at least one mutation in the tyrosine kinases; sampling of colorect cancer cells suggest an important role of MLK4 in this process.
Other Names:
Mitogen-activated protein kinase kinase kinase MLK4, Mixed lineage kinase 4, MLK4 {ECO:0000303|Ref1}
Target/Specificity:
This MLK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human MLK4.
Antigen Region:
33-62
Antigen Type: Synthetic Peptide
Gene Name: MAP3K21 (HGNC:29798)
Gene ID: 84451
Primary Accession: Q5TCX8
NCBI Accession: NP_115811.2
Other Accession: Q8VDG6
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Mixed-lineage kinases (MLKs) function as mitogen-activated protein kinase kinase kinases (MAP3Ks), activating the p38 and JNK signaling cascades. Systematic mutational analyses of tyrosine kinases reveal that a minimum of 30% of colorectal cancer contain at least one mutation in the tyrosine kinases; sampling of colorect cancer cells suggest an important role of MLK4 in this process.
Other Names:
Mitogen-activated protein kinase kinase kinase MLK4, Mixed lineage kinase 4, MLK4 {ECO:0000303|Ref1}
Target/Specificity:
This MLK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human MLK4.
Antigen Region:
33-62
Antigen Type: Synthetic Peptide
Gene Name: MAP3K21 (HGNC:29798)
Gene ID: 84451
Primary Accession: Q5TCX8
NCBI Accession: NP_115811.2
Other Accession: Q8VDG6
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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