MLL2 polyclonal antibody, anti-human, mouse, rat

Background:
The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome.

Research Area: Epigenetics and nuclear signaling

Synonyms: Histone-lysine N-methyltransferase MLL2 , EC 2.1.1.43, ALL1-related protein, Lysine N-methyltransferase 2D, KMT2D, Myeloid/lymphoid or mixed-lineage leukemia protein 2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year