MLLT1 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP6188a
Catalog Number: AC-AP6188a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1927/1928
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1927/1928
Applications: WB
Datasheet
Request Information
Background:
Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11;19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.
Other Names:
Protein ENL, YEATS domain-containing protein 1, MLLT1, ENL, LTG19, YEATS1
Target/Specificity:
This MLLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 523-552 amino acids from the C-terminal region of human MLLT1.
Antigen Region:
523-552
Antigen Type: Synthetic Peptide
Gene Name: MLLT1
Gene ID: 4298
Primary Accession: Q03111
NCBI Accession: NP_005925.2
Other Accession: NP_005925
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11;19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.
Other Names:
Protein ENL, YEATS domain-containing protein 1, MLLT1, ENL, LTG19, YEATS1
Target/Specificity:
This MLLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 523-552 amino acids from the C-terminal region of human MLLT1.
Antigen Region:
523-552
Antigen Type: Synthetic Peptide
Gene Name: MLLT1
Gene ID: 4298
Primary Accession: Q03111
NCBI Accession: NP_005925.2
Other Accession: NP_005925
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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