MLXIPL polyclonal, anti-human, mouse, rat

Background:
This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants.

Synonyms: MIO, CHREBP, MONDOB, WBSCR14, WS-bHLH, bHLHd14

Cellular Location: Nucleus

Immunogen:
A synthetic peptide of human MLXIPL

Gene Symbol: MLXIPL

Gene ID: 51085

Swiss prot: Q9NP71

Calculated MW: 93/62/78kDa

Recommended dilution:
IHC 1:20-100

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.