MMP-1 polyclonal, anti-human antibody
€275.00
In stock
SKU
AC-ABV11067-100
Catalog Number: AC-ABV11067-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within the extracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases, stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to be cleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are tho µght to play an important role in tissue remodeling associated with various physiological and pathological processes. MMP1 cleaves collagens of types I, II, III, VII and X. MMP1 is tho µght to play an important role in rheumatoid and osteo-arthritis pathogenesis as mediators of cartilage and bone destruction.
Other Names:
Interstitial collagenase, 3.4.24.7, Fibroblast collagenase, Matrix metalloproteinase-1, MMP-1, 22 kDa interstitial collagenase, 27 kDa interstitial collagenase, MMP1, CLG
Primary Accession: P03956
Gene Name: MMP1
Gene ID: 4312
Concentration (mg/ml): 0.5 mg/ml
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within the extracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases, stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to be cleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are tho µght to play an important role in tissue remodeling associated with various physiological and pathological processes. MMP1 cleaves collagens of types I, II, III, VII and X. MMP1 is tho µght to play an important role in rheumatoid and osteo-arthritis pathogenesis as mediators of cartilage and bone destruction.
Other Names:
Interstitial collagenase, 3.4.24.7, Fibroblast collagenase, Matrix metalloproteinase-1, MMP-1, 22 kDa interstitial collagenase, 27 kDa interstitial collagenase, MMP1, CLG
Primary Accession: P03956
Gene Name: MMP1
Gene ID: 4312
Concentration (mg/ml): 0.5 mg/ml
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