MMP-1 polyclonal, anti-human, rabbit, bovine, horse, guinea pig, hamster, xenopus, pig

MMP-1 polyclonal, anti-human, rabbit, bovine, horse, guinea pig, hamster, xenopus, pig

€422.00
In stock
SKU
250749
Catalog Nr.: 250749
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Datasheet
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Protein Family: CAM Ligands, Enzymes, Peptidases

Pathway and Disease: Cancers, Endocrine System

Description:
Matrix metalloproteinase family members are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Matrix metalloproteinase-1 (Interstitial collagenase A/B or MMP-1) cleaves collagens of types I, II and III. This antibody detects human MMP-1 but not mouse or rat MMP-1.

Alternate Names: Interstitial collagenase, Matrix metalloproteinase-1, MMP-1, MMP1, CLG

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: P03956

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the TIMP1 binding site and substrate recognition site in the C-term region of human MMP-1.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Product Citations:
[1] Frara N et al. 2016. BMC Musculoskelet Disord. 17:34. PMID 26781840.
[2] Sousa NG et al. 2014. Arch Oral Biol. 59(9): 944-53. PMID 24927330.
[3] Yang S et al. 2011. J Cell Biochemistry. 112(9):2454-2462. PMID 21538481.
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