MMP-11 Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES2803
Catalog Number: ELK-ES2803
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, IF, ELISA
Information
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Questions? Contact us!
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, IF, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Background:
matrix metallopeptidase 11(MMP11) Homo sapiens Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008],
Alternative Names:
MMP11, STMY3, Stromelysin-3, SL-3, ST3, Matrix metalloproteinase-11, MMP-11
Immunogen: The antiserum was produced against synthesized peptide derived from human MMP-11. AA range:61-110
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 60
GeneID: MMP11
Storage: -20°C/1 year
NOTE: For Research Use Only
matrix metallopeptidase 11(MMP11) Homo sapiens Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008],
Alternative Names:
MMP11, STMY3, Stromelysin-3, SL-3, ST3, Matrix metalloproteinase-11, MMP-11
Immunogen: The antiserum was produced against synthesized peptide derived from human MMP-11. AA range:61-110
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 60
GeneID: MMP11
Storage: -20°C/1 year
NOTE: For Research Use Only
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