MMP-13 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6668
Background:
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibroPVRL1, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-13 (also designated collagenase-3) is produced by breast carcinomas and degrades collagen types I, II and III. MMP-13 has wide substrate specificity, and its physiologic expression is limited to situations in which rapid and effective remodeling of collagenous ECM takes place, such as fetal bone development and adult bone remodeling.
Alternative Name:
Collagenase 3, Collagenase 3, Collagenase3, MANDP1, Matrix metallopeptidase 13 (collagenase 3), Matrix Metalloproteinase 13, Matrix Metalloproteinase 13, Matrix metalloproteinase-13, MMP 13, MMP-13, Mmp13,
Application Dilution: WB: 1:500 - 1:2000
Specificity: MMP-13 polyclonal antibody detects endogenous levels of ~60 kDa latent or the ~48 kDa active forms of MMP-13 protein.
Immunogen:
Recombinant full length Human MMP-13.
MW: ~ 48, 60 kDa
Swis Prot.: P45452
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibroPVRL1, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-13 (also designated collagenase-3) is produced by breast carcinomas and degrades collagen types I, II and III. MMP-13 has wide substrate specificity, and its physiologic expression is limited to situations in which rapid and effective remodeling of collagenous ECM takes place, such as fetal bone development and adult bone remodeling.
Alternative Name:
Collagenase 3, Collagenase 3, Collagenase3, MANDP1, Matrix metallopeptidase 13 (collagenase 3), Matrix Metalloproteinase 13, Matrix Metalloproteinase 13, Matrix metalloproteinase-13, MMP 13, MMP-13, Mmp13,
Application Dilution: WB: 1:500 - 1:2000
Specificity: MMP-13 polyclonal antibody detects endogenous levels of ~60 kDa latent or the ~48 kDa active forms of MMP-13 protein.
Immunogen:
Recombinant full length Human MMP-13.
MW: ~ 48, 60 kDa
Swis Prot.: P45452
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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