MMP-7 polyclonal, anti-mouse, rat antibody
€310.00
In stock
SKU
AC-ABO10790
Catalog Number: AC-ABO10790
Size: 100 µg
Host: rabbit IgG
Applications: WB, IHC-P
Datasheet
Request Information
Size: 100 µg
Host: rabbit IgG
Applications: WB, IHC-P
Datasheet
Request Information
Description: Rabbit IgG polyclonal antibody for DNA excision repair protein ERCC-6 (ERCC6) detection. Tested with WB in human, rat.
Protein Name: DNA excision repair protein ERCC-6
Background:
Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex (DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II- blocking lesions. .
Other Names:
DNA excision repair protein ERCC-6, 3.6.4.-, ATP-dependent helicase ERCC6, Cockayne syndrome protein CSB, ERCC6, CSB
Subcellular Localization: Nucleus .
Gene ID: 2074
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CSB (160-205aa QAATSRDINRKLDSVKRQKYNKEQQLKKITAKQKHLQAILGGAEVK).
Calculated MW: 168416
Purification: Immunogen affinity purified.
Format: Lyophilized
Contents: Each vial contains 5mg BSA, 0.9 mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.
Concentration (mg/ml): Add 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Protein Name: DNA excision repair protein ERCC-6
Background:
Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex (DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II- blocking lesions. .
Other Names:
DNA excision repair protein ERCC-6, 3.6.4.-, ATP-dependent helicase ERCC6, Cockayne syndrome protein CSB, ERCC6, CSB
Subcellular Localization: Nucleus .
Gene ID: 2074
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CSB (160-205aa QAATSRDINRKLDSVKRQKYNKEQQLKKITAKQKHLQAILGGAEVK).
Calculated MW: 168416
Purification: Immunogen affinity purified.
Format: Lyophilized
Contents: Each vial contains 5mg BSA, 0.9 mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.
Concentration (mg/ml): Add 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
| Is Featured? | No |
|---|
Write Your Own Review