MMP-9 polyclonal, anti-human, mouse, rat antibody

Background:
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92-kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption.

Other Names:
GELB , EC 3.4.24.35 , CLG4B , Matrix metalloproteinase

Primary Accession: P14780

Other Accession: AAM97934

Gene Name: MMP9

Gene ID: 4318

Concentration (mg/ml): 0.5 mg/ml