MMP1 polyclonal, anti-human

Quantity: 100 µg

Background:
Matrix metalloproteinase-1 (MMP-1), also known as interstitial collagenase and fibroblast collagenase, is an enzyme that in humans is encoded by the MMP1 gene. MMP-1 was the first vertebrate collagenase both purified to homogeneity as a protein, and cloned as a cDNA. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. It is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

Description:
Rabbit IgG polyclonal antibody for Interstitial collagenase (MMP1) detection. Tested with WB in Human.

Synonyms:
27 kDa interstitial collagenase antibody, CLG antibody, CLGN antibody, collagenase, fibroblast antibody, collagenase, interstitial antibody, Fibroblast collagenase antibody, Interstitial collagenase antibody, Matrix metallopeptidase 1 (interstitial collagenase) antibody, Matrix metalloprotease 1 antibody, Matrix Metalloproteinase 1 antibody, Matrix metalloproteinase-1 antibody, MMP 1 antibody, MMP-1 antibody, MMP1 antibody, MMP1_HUMAN antibody, OTTHUMP00000045866 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human MMP1 (194-231aa DAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTD).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.