MMP1 Polyclonal Antibody

Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Cell Biology, Cardiovascular, Signal Transduction

Synonyms:
27 kDa interstitial collagenase, CLG, CLGN, collagenase, fibroblast, collagenase, interstitial, Fibroblast collagenase, Interstitial collagenase, Matrix metallopeptidase 1 (interstitial collagenase), Matrix metalloprotease 1, Matrix Metalloproteinase 1, Matrix metalloproteinase-1, MMP 1, MMP-1, MMP1, MMP1, OTTHUMP00000045866

Immunogen: Recombinant protein of human MMP1

Swissprot: P03956
Gene Accession: BC013875

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-6837/sc-12348/sc-30069

Citation(s):
https://www.sciencedirect.com/science/article/pii/S0753332218350662