MMP1 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP11874c
Catalog Number: AC-AP11874c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18908
Applications: IF, IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18908
Applications: IF, IHC-P, WB
Datasheet
Request Information
Background:
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. This gene encodes a secreted enzymewhich breaks down the interstitial collagens, types I, II, and III.The gene is part of a cluster of MMP genes which localize tochromosome 11q22.3. Alternative splicing results in multipletranscript variants.
Other Names:
Interstitial collagenase, Fibroblast collagenase, Matrix metalloproteinase-1, MMP-1, 22 kDa interstitial collagenase, 27 kDa interstitial collagenase, MMP1, CLG
Target/Specificity:
This MMP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-347 amino acids from the Central region of human MMP1.
Antigen Region:
317-347
Antigen Type: Synthetic Peptide
Gene Name: MMP1
Gene ID: 4312
Primary Accession: P03956
NCBI Accession: NP_002412.1
Other Accession: NP_002412
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. This gene encodes a secreted enzymewhich breaks down the interstitial collagens, types I, II, and III.The gene is part of a cluster of MMP genes which localize tochromosome 11q22.3. Alternative splicing results in multipletranscript variants.
Other Names:
Interstitial collagenase, Fibroblast collagenase, Matrix metalloproteinase-1, MMP-1, 22 kDa interstitial collagenase, 27 kDa interstitial collagenase, MMP1, CLG
Target/Specificity:
This MMP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-347 amino acids from the Central region of human MMP1.
Antigen Region:
317-347
Antigen Type: Synthetic Peptide
Gene Name: MMP1
Gene ID: 4312
Primary Accession: P03956
NCBI Accession: NP_002412.1
Other Accession: NP_002412
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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