MMP11 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP13729B
Catalog Number: AC-AP13729B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33704
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33704
Applications: IHC-P, WB
Datasheet
Request Information
Background:
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. However, the enzyme encoded by thisgene is activated intracellularly by furin within the constitutivesecretory pathway. Also in contrast to other MMP's, this enzymecleaves alpha 1-proteinase inhibitor but weakly degrades structuralproteins of the extracellular matrix.
Other Names:
Stromelysin-3, SL-3, ST3, 3424-, Matrix metalloproteinase-11, MMP-11, MMP11, STMY3
Target/Specificity:
This MMP11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the C-terminal region of human MMP11.
Antigen Region:
399-428
Antigen Type: Synthetic Peptide
Gene Name: MMP11
Gene ID: 4320
Primary Accession: P24347
NCBI Accession: NP_005931.2
Other Accession: NP_005931.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. However, the enzyme encoded by thisgene is activated intracellularly by furin within the constitutivesecretory pathway. Also in contrast to other MMP's, this enzymecleaves alpha 1-proteinase inhibitor but weakly degrades structuralproteins of the extracellular matrix.
Other Names:
Stromelysin-3, SL-3, ST3, 3424-, Matrix metalloproteinase-11, MMP-11, MMP11, STMY3
Target/Specificity:
This MMP11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the C-terminal region of human MMP11.
Antigen Region:
399-428
Antigen Type: Synthetic Peptide
Gene Name: MMP11
Gene ID: 4320
Primary Accession: P24347
NCBI Accession: NP_005931.2
Other Accession: NP_005931.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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