MMP11 polyclonal (C-term), anti-human, mouse
€0.00
In stock
SKU
AC-AP6195a
Catalog Number: AC-AP6195a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2023
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2023
Applications: WB
Datasheet
Request Information
Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP11 may play an important role in the progression of epithelial malignancies. It is specifically expressed in stromal cells of breast carcinomas.
Other Names:
Stromelysin-3, SL-3, ST3, 3424-, Matrix metalloproteinase-11, MMP-11, MMP11, STMY3
Target/Specificity:
This MMP11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 398-426 amino acids from the C-terminal region of human MMP11.
Antigen Region:
398-426
Antigen Type: Synthetic Peptide
Gene Name: MMP11
Gene ID: 4320
Primary Accession: P24347
NCBI Accession: NP_005931.2
Other Accession: NP_005931
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP11 may play an important role in the progression of epithelial malignancies. It is specifically expressed in stromal cells of breast carcinomas.
Other Names:
Stromelysin-3, SL-3, ST3, 3424-, Matrix metalloproteinase-11, MMP-11, MMP11, STMY3
Target/Specificity:
This MMP11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 398-426 amino acids from the C-terminal region of human MMP11.
Antigen Region:
398-426
Antigen Type: Synthetic Peptide
Gene Name: MMP11
Gene ID: 4320
Primary Accession: P24347
NCBI Accession: NP_005931.2
Other Accession: NP_005931
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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