MMP12 polyclonal, anti-human

Quantity: 100 µg

Background:
Matrix metalloproteinase-12(MMP12), also known as MME or ME, is an enzyme that in humans is encoded by the MMP12 gene. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.2. It is though that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. This gene may involved in tissue injury and remodeling.

Description:
Rabbit IgG polyclonal antibody for Macrophage metalloelastase (MMP12) detection. Tested with WB in Human.

Synonyms:
EC 3.4.24.65 antibody, HME antibody, Macrophage elastase antibody, Macrophage metalloelastase antibody, Macrophage metaloelastase antibody, Matrix metallopeptidase 12(macrophage elastase) antibody, Matrix metalloprotease 12 antibody, Matrix metalloproteinase-12 antibody, ME antibody, MGC138506 antibody, MME antibody, MMP 12 antibody, MMP-12 antibody, Mmp12 antibody, MMP12_HUMAN antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human MMP12(428-444aa KIDAVFYSKNKYYYFFQ).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.