MMP12 rabbit polyclonal, anti-human

Backgroud: MMP-12 lacks a transmembrane domain and furin cleavage site. The zymogen for MMP-12 is about 54 kDa, and is quickly activated to the 45 kDa form, and this breaks down to cascade of active forms, ending with the common 22 kDa form.Stimulated macrophages produce MMP-12; it has also been found in osteosarcoma cells, synovial fibroblasts and lung fibroblasts.

Synonyms: Macrophage metalloelastase, MME, 3.4.24.65, Macrophage elastase, ME, hME, Matrix metalloproteinase-12, MMP-12, MMP12, HME

Gene Name: MMP12

Gene ID: 4321

SwissProt ID: P39900

Purification: Affinity Chromatography

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.