MMP13 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP13706c
Catalog Number: AC-AP13706c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33646
Applications: IHC-P, IF, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33646
Applications: IHC-P, IF, WB
Datasheet
Request Information
Background:
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. The protein encoded by this genecleaves type II collagen more efficiently than types I and III. Itmay be involved in articular cartilage turnover and cartilagepathophysiology associated with osteoarthritis. The gene is part ofa cluster of MMP genes which localize to chromosome 11q22.3.
Other Names:
Collagenase 3, 3424-, Matrix metalloproteinase-13, MMP-13, MMP13
Target/Specificity:
This MMP13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-282 amino acids from the Central region of human MMP13.
Antigen Region:
253-282
Antigen Type: Synthetic Peptide
Gene Name: MMP13
Gene ID: 4322
Primary Accession: P45452
NCBI Accession: NP_002418.1
Other Accession: O62806; NP_002418.1; O18927
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. The protein encoded by this genecleaves type II collagen more efficiently than types I and III. Itmay be involved in articular cartilage turnover and cartilagepathophysiology associated with osteoarthritis. The gene is part ofa cluster of MMP genes which localize to chromosome 11q22.3.
Other Names:
Collagenase 3, 3424-, Matrix metalloproteinase-13, MMP-13, MMP13
Target/Specificity:
This MMP13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-282 amino acids from the Central region of human MMP13.
Antigen Region:
253-282
Antigen Type: Synthetic Peptide
Gene Name: MMP13
Gene ID: 4322
Primary Accession: P45452
NCBI Accession: NP_002418.1
Other Accession: O62806; NP_002418.1; O18927
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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