MMP14 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Matrix metalloproteinase-14, also called MT-MMP 1, is an enzyme that in humans is encoded by the MMP14 gene. The protein encoded by this gene is a member of the membrane-type MMP subfamily. This gene is mapped to 14q11.2. Proteins of the matrix metalloproteinase(MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene may be involved in actin cytoskeleton reorganization by cleaving PTK7. It acts as a positive regulator of cell growth and migration via activation of MMP15.

Description:
Rabbit IgG polyclonal antibody for Matrix metalloproteinase-14 (MMP14) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
Matrix metallopeptidase 14(membrane inserted) antibody, Matrix metalloproteinase 14 antibody, Matrix metalloproteinase-14 antibody, Membrane type 1 matrix metalloproteinase antibody, Membrane type 1 metalloprotease antibody, Membrane type matrix metalloproteinase 1 antibody, Membrane-type matrix metalloproteinase 1 antibody, Membrane-type-1 matrix metalloproteinase antibody, MMP 14 antibody, MMP X1 antibody, MMP-14 antibody, MMP-X1 antibody, Mmp14 antibody, MMP14_HUMAN antibody, MMPX1 antibody, MT MMP 1 antibody, MT-MMP 1 antibody, MT1 MMP antibody, MT1-MMP antibody, MT1MMP antibody, MTMMP 1 antibody, MTMMP1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human MMP14(567-582aa TPRRLLYCQRSLLDKV), different from the related mouse and rat sequences by one amino acid.A synthetic peptide corresponding to a sequence at the C-terminus of human MMP14(567-582aa TPRRLLYCQRSLLDKV), different from the related mouse and rat sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.