MMP14 polyclonal (C-term), anti-human
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In stock
SKU
AC-AP19882b
Catalog Number: AC-AP19882b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB41662
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB41662
Applications: WB
Datasheet
Request Information
Background:
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. However, the protein encoded by thisgene is a member of the membrane-type MMP (MT-MMP) subfamily; eachmember of this subfamily contains a potential transmembrane domainsuggesting that these proteins are expressed at the cell surfacerather than secreted. This protein activates MMP2 protein, and thisactivity may be involved in tumor invasion.
Other Names:
Matrix metalloproteinase-14, MMP-14, MMP-X1, Membrane-type matrix metalloproteinase 1, MT-MMP 1, MTMMP1, Membrane-type-1 matrix metalloproteinase, MT1-MMP, MT1MMP, MMP14
Target/Specificity:
This MMP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 495-523 amino acids from the C-terminal region of human MMP14.
Antigen Region:
495-523
Antigen Type: Synthetic Peptide
Gene Name: MMP14
Gene ID: 4323
Primary Accession: P50281
NCBI Accession: NP_004986.1
Other Accession: Q10739; Q9XT90; P53690; NP_004986.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. However, the protein encoded by thisgene is a member of the membrane-type MMP (MT-MMP) subfamily; eachmember of this subfamily contains a potential transmembrane domainsuggesting that these proteins are expressed at the cell surfacerather than secreted. This protein activates MMP2 protein, and thisactivity may be involved in tumor invasion.
Other Names:
Matrix metalloproteinase-14, MMP-14, MMP-X1, Membrane-type matrix metalloproteinase 1, MT-MMP 1, MTMMP1, Membrane-type-1 matrix metalloproteinase, MT1-MMP, MT1MMP, MMP14
Target/Specificity:
This MMP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 495-523 amino acids from the C-terminal region of human MMP14.
Antigen Region:
495-523
Antigen Type: Synthetic Peptide
Gene Name: MMP14
Gene ID: 4323
Primary Accession: P50281
NCBI Accession: NP_004986.1
Other Accession: Q10739; Q9XT90; P53690; NP_004986.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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