MMP15 polyclonal (N-term), anti-human
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In stock
SKU
AC-AP13751a
Catalog Number: AC-AP13751a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33746
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33746
Applications: IHC-P, WB
Datasheet
Request Information
Background:
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. However, the protein encoded by thisgene is a member of the membrane-type MMP (MT-MMP) subfamily; eachmember of this subfamily contains a potential transmembrane domainsuggesting that these proteins are expressed at the cell surfacerather than secreted.
Other Names:
Matrix metalloproteinase-15, MMP-15, 3424-, Membrane-type matrix metalloproteinase 2, MT-MMP 2, MTMMP2, Membrane-type-2 matrix metalloproteinase, MT2-MMP, MT2MMP, SMCP-2, MMP15
Target/Specificity:
This MMP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-196 amino acids from the N-terminal region of human MMP15.
Antigen Region:
168-196
Antigen Type: Synthetic Peptide
Gene Name: MMP15
Gene ID: 4324
Primary Accession: P51511
NCBI Accession: NP_002419.1
Other Accession: NP_002419.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. However, the protein encoded by thisgene is a member of the membrane-type MMP (MT-MMP) subfamily; eachmember of this subfamily contains a potential transmembrane domainsuggesting that these proteins are expressed at the cell surfacerather than secreted.
Other Names:
Matrix metalloproteinase-15, MMP-15, 3424-, Membrane-type matrix metalloproteinase 2, MT-MMP 2, MTMMP2, Membrane-type-2 matrix metalloproteinase, MT2-MMP, MT2MMP, SMCP-2, MMP15
Target/Specificity:
This MMP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-196 amino acids from the N-terminal region of human MMP15.
Antigen Region:
168-196
Antigen Type: Synthetic Peptide
Gene Name: MMP15
Gene ID: 4324
Primary Accession: P51511
NCBI Accession: NP_002419.1
Other Accession: NP_002419.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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