MMP16 polyclonal (N-term), anti-human

MMP16 polyclonal (N-term), anti-human

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In stock
SKU
AC-AP6200a
Catalog Number: AC-AP6200a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2031
Applications: WB, IHC-P
Datasheet

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Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene for MMP16 produces two transcripts, which encode a membrane-bound form and a soluble form of the protein. Both forms of the protein activate MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.

Other Names:
Matrix metalloproteinase-16, MMP-16, 3424-, MMP-X2, Membrane-type matrix metalloproteinase 3, MT-MMP 3, MTMMP3, Membrane-type-3 matrix metalloproteinase, MT3-MMP, MT3MMP, MMP16, MMPX2

Target/Specificity:
This MMP16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the N-terminal region of human MMP16.

Antigen Region:
154-183

Antigen Type: Synthetic Peptide

Gene Name: MMP16 (HGNC:7162)
Gene ID: 4325
Primary Accession: P51512
NCBI Accession: NP_005932.2
Other Accession: O35548; Q9WTR0; NP_072086
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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