MMP17 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13995b
Background:
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. The protein encoded by this gene isconsidered a member of the membrane-type MMP (MT-MMP) subfamily.However, this protein is unique among the MT-MMP's in that it is aGPI-anchored protein rather than a transmembrane protein. Theprotein activates MMP-2 by cleavage.
Other Names:
Matrix metalloproteinase-17, MMP-17, 3424-, Membrane-type matrix metalloproteinase 4, MT-MMP 4, MTMMP4, Membrane-type-4 matrix metalloproteinase, MT4-MMP, MT4MMP, MMP17, MT4MMP
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13995b was selected from the C-term region of MMP17. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MMP17
Gene ID: 4326
Primary Accession: Q9ULZ9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. The protein encoded by this gene isconsidered a member of the membrane-type MMP (MT-MMP) subfamily.However, this protein is unique among the MT-MMP's in that it is aGPI-anchored protein rather than a transmembrane protein. Theprotein activates MMP-2 by cleavage.
Other Names:
Matrix metalloproteinase-17, MMP-17, 3424-, Membrane-type matrix metalloproteinase 4, MT-MMP 4, MTMMP4, Membrane-type-4 matrix metalloproteinase, MT4-MMP, MT4MMP, MMP17, MT4MMP
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13995b was selected from the C-term region of MMP17. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MMP17
Gene ID: 4326
Primary Accession: Q9ULZ9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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