MMP17 Polyclonal Antibody

Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.

Research Area: Cancer, Cell Biology, Cardiovascular, Signal Transduction

Synonyms:
Matrix metalloproteinase 17, Matrix metalloproteinase 17 membrane inserted, Matrix metalloproteinase-17, Membrane type 4 matrix metalloproteinase, Membrane type matrix metalloproteinase 4, Membrane-type matrix metalloproteinase 4, Membrane-type-4 matrix metalloproteinase, MMP 17, MMP-17, Mmp17, MMP17, MT MMP 4, MT MMP4, MT-MMP 4, MT4 MMP, MT4-MMP, MT4MMP, MTMMP 4, MTMMP4

Immunogen: Synthetic peptide of human MMP17

Swissprot: Q9ULZ9
Gene Accession: NP_057239

Calculated MW: 58 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-8847/sc-20909/sc-13972